Abstract: A novel melamine magnetic molecularly imprinted polymer(Fe3O4-GO@SiO2@MIP) was prepared based on graphene oxide(GO) using melamine(MEL) as the template molecule, methacrylic acid(MAA) as the functional monomer and ethylene glycol dimethacrylate(EGDMA) as the cross-linker. The Fe3O4-GO@SiO2@MIP was characterized by scanning electron microscope(SEM), transmission electron microscope(TEM), thermogravimetric analysis(TGA) and vibrating sample magnetometer(VSM). The results showed that MEL imprinted layer was grafted on magnetic GO surface successfully. The adsorption properties were investigated by high performance liquid chromatography, and the results demonstrated that the Fe3O4-GO@SiO2@MIP exhibited specific selectivity towards MEL. The maximum adsorption capacity of Fe3O4-GO@SiO2@MIP is 33.11 mg/g, and the selectivity factor of MEL towards CYR and CYA is 2.43 and 2.84, respectively. Combined with magnetic solid phase extraction(M-SPE) and high-performance liquid chromatography with the imprinted material as stationary phase, melamine from the sample solution of milk was successfully separated, enriched and detected.
Template and target information: melamine
Author keywords: imprinted polymer, Melamine, magnetic graphene oxide, Magnetic solid phase extraction, high-performance liquid chromatography