Reference type: Journal
Authors: de B.Peçanha BR, Dias LRS, Spinelli E, Muri EMF
Article Title: Molecularly imprinted polymers prepared by precipitation polymerization and their application to solid phase extraction (Polímeros de Impressão Molecular Obtidos Através de Polimerização por Precipitação e sua Aplicação na Técnica de Extração em Fase Sólida).
Publication date: 2013
Journal: Polimeros
Volume: 23
Issue: (4)
Page numbers: 509-513.
DOI: 10.4322/polimeros.2013.055

Abstract: Molecularly imprinted polymers (MIPs) were synthesized and applied as adsorbents in the solid-phase extraction (SPE) technique. The polymers were synthesized by precipitation polymerization because of its simplicity, high yields and good control of final particle size. MIPs were synthesized using methacrylic acid as functional monomer, trimethylolpropane trimethacrylate as crosslinker and amiloride hydrochloride as template. The polar solvent mixture used (THF:MeOH:H2O) permitted polar molecules such as amiloride hydrochloride to be used. The solvent volume control allowed bigger particles to be formed, so that the solid-phase extraction technique could be employed under usual conditions, and therefore this polymerization technique is promising for preparing adsorbents for SPE
Template and target information: amiloride hydrochloride
Author keywords: Amiloride hydrochloride, molecularly imprinted polymers (MIPs), Precipitation polymerization method, Solid-phase extraction technique (SPE)