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Reference type: Journal
Authors: Cennamo N, D'Agostino G, Pesavento M, Zeni L
Article Title: High selectivity and sensitivity sensor based on MIP and SPR in tapered plastic optical fibers for the detection of l-nicotine.
Publication date: 2014
Journal: Sensors and Actuators B: Chemical
Volume: 191
Page numbers: 529-536.
DOI: 10.1016/j.snb.2013.10.067
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400513012537

Abstract: A biomimetic sensor based on molecularly imprinted polymer (MIP) and surface plasmon resonance (SPR) transduction, in connection with tapered plastic optical fiber (POF), has been developed for the marker-free, direct and selective detection of low molecular weight substances. The device has been experimentally tested for l-nicotine ((-)-1-methyl-2-(3-pyridyl)pyrrolidine, MW = 162.24). The sensor system developed made the selective and fast detection of l-nicotine possible, with a low cost, easy to realize and small sample volume procedure. The sensor can discriminate between l- and d-nicotine. The linearity range was from 0 to 10-3 M, and the sensitivity strongly depended on the characteristics of the tapered fiber, ranging from 1.3 x 10^4 nm/M, for a taper ratio 1.8, to 1.7 x 10^3 nm/M for a taper ratio 1, i.e. a not-tapered fiber
Template and target information: l-nicotine, nicotine
Author keywords: optical biosensor, surface plasmon resonance, Tapered plastic optical fiber, Molecularly imprinted polymers, L-nicotine

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