Authors: Sabourin L
, Ansell RJ
, Mosbach K
, Nicholls IA
Molecularly imprinted polymer combinatorial libraries for multiple simultaneous chiral separations.
Publication date: 1998
Journal: Analytical Communications
Abstract: We demonstrate that the ligand cross-reactivities of molecularly imprinted polymers can be beneficially employed for the simultaneous separation of different stereoisomeric structures. In this study, a limited molecularly imprinted polymer combinatorial library has been prepared and used for the simultaneous separation of a mixture of N- tert-butyloxycarbonyl-L-phenylalanine, N-tert-butyloxycarbonyl-D- phenylalanine N-acetyl-L-phenylalaninyl-L-tryptophanyl methyl ester, N-acetyl-D-phenylalaninyl-D-tryptophanyl methyl ester, yohimbine and corynanthine
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