Inventors: Miyata T, Uragami T
Patent Title: Molecular imprint gel, its manufacturing method, measuring method for object molecule in specimen using molecular imprint gel, and reagent for object molecule measurement
Publication date: 2008
Publication number: JP2006-138656

Abstract: PROBLEM TO BE SOLVED: To provide a simply manufactured molecular imprint gel for measuring object molecules in a specimen with high sensitivity. SOLUTION: This molecular imprint gel is manufactured through the following processes: (1) a process for separately reacting two or more ligands in respect to the object molecules with a monomer or polymer serving as a material for the gel to manufacture ligand-introduced monomers or ligand-introduced polymers corresponding to the number of ligands, (2) a process for reacting all the ligands of the introduced-monomers or introduced-polymers manufactured through the process (1) with the object molecules to form a complex of these with the object molecules, (3) a process for forming a high-polymer network by reacting the complex manufactured through the process (2) with a molecular cross-linker to manufacture a gel including the complex of the ligands with the object molecules, and (4) a process for removing the object molecules from the gel manufactured through the process (3).
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