Inventors: Zhang DB, Wu AB, Song SQ
Patent Title: Method for purifying erythromycin by using molecular engram polymer
Publication date: 2008
Publication number: CN101148464

Abstract: The present invention relates to biological technology, and is especially process of purifying erythromycin with erythromycin molecular engram polymer. The process includes the following steps: 1. dissolving the mixture of template molecule erythromycin, functional monomer methacrylic acid and cross-linking agent ethylene glycol dimethacrylate in pore creating agent, adding initiator and sealing; 2. grinding the synthesized polymer, eliminating fine grains and extracting to eliminate template molecule; 3. drying the polymer with the template molecule eliminated at 60 for a night to obtain erythromycin molecular engram polymer; 4. filling the erythromycin molecular engram polymer into solid extracting column tube; and 5. activating the solid extracting column, adding animal tissue extracting liquid or water sample dissolving in 40 % concentration methanol solution, and eluting the solid extracting column to elute and purify erythromycin.
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