Inventors: Perollier C, Naraghi K, Bayoudh S
Patent Title: Method for producing a radioactive tracer
Publication date: 2011
Publication number: WO/2011/110994

Abstract: The present invention relates to a method for preparing a radioactive tracer provided with a radioactive fluorine isotope, including at least the following steps consisting in: i) providing a precursor of the radioactive tracer, comprising at least one leaving group completely or partially formed by a labelling entity, wherein said leaving group can be moved by a fluoride ion; ii) providing a molecularly imprinted polymer dedicated to the molecular recognition of at least the aforementioned labelling entity; iii) exposing the precursor to a radioactive fluoride ion source under conditions suitable for the movement of the leaving group by a radioactive fluoride ion; iv) placing the mixture resulting from step (iii) in contact with the molecularly imprinted polymer under conditions suitable for the recognition of the labelling entity; and v) obtaining a solution containing the radioactive tracer provided with a radioactive isotope of fluorine obtained at the end of step (iii).
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110915&DB=EPODOC&locale=en_gb&CC=WO&NR=2011110994A1&KC=A1