Inventors: Lei JD, Ma GH, Su ZG, Kou X, Geng LY
Patent Title: Method for preparing molecularly imprinted polymer nano-microspheres with uniform size and application thereof
Publication date: 2012
Publication number: CN102380359

Abstract: The invention discloses a molecularly imprinted polymer nano-microsphere with average grain size of 200 nm to 100 microns and with grain size distribution coefficient C.V. of not more than 20%. The preparation method comprises the following steps of: firstly, mixing a dispersed-phase solution containing template molecules and a continuous-phase solution to obtain an original emulsion; secondly, filtering the original emulsion by a microporous membrane at a preset pressure to obtain an emulsion with uniform grain size; thirdly, performing cross-linking polymerization on the emulsion in nitrogen to obtain polymer nano-microspheres; fourthly, washing the obtained polymer nano-microspheres to remove template molecules and non-reacted functional monomers in the polymer; and finally, obtaining the molecularly imprinted polymer nano-microspheres with uniform size.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120321&DB=EPODOC&locale=en_EP&CC=CN&NR=102380359A&KC=A&ND=1