Inventors: Zhang HQ, Pan GQ, Zhang Y
Patent Title: Surface-hydrophilic molecularly imprinted polymer microsphere and preparation method thereof
Publication date: 2011
Publication number: CN102059104

Abstract: The invention relates to a surface-hydrophilic molecularly imprinted polymer microsphere and a preparation method thereof. The molecularly imprinted polymer microsphere has the crosslinking degree of over 60 percent and a grain size of 1 to 5mu m. The surface of the microsphere is provided with a hydrophilic polymer brush, and the microsphere has excellent molecular recognition performance on template molecules in a pure aqueous solution system. The microspheres are synthesized by a two-step process in reversible addition fragmentation chain transfer (RAFT) controlled free radical polymerization technology. The invention has the advantages of simple synthesis method, wide application range, pure products and the like. The prepared molecularly imprinted polymer microsphere has a wide application prospect in the fields of chromatographic stationary phases, biological sample analysis, medically clinical immunoassay, food and environment monitoring, mimic enzyme catalysis, bionic sensors and the like.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110518&DB=EPODOC&locale=en_EP&CC=CN&NR=102059104A&KC=A&ND=4