Inventors: Lee ES,
Nunna BB
Patent Title: Biomarker detection and self-separation of serum during capillary flow
Publication date: 2018
Publication number: US20180128823
Abstract: Molecularly Imprinted Polymers (MIPs) are utilized to detect diseases and minimize false negative/positive scenarios. MIPs are implemented on a nano-electric circuit in a biochip where interactions of MIPs and an Antigen/Antibody (AG/AB) are detected, and disease specific biomarkers diagnosed. Biomarker detection is achieved with interdigitated gold electrodes in a biochip's microchannel. Capacitance changes due to biomarker interaction with AG/AB electrode coating diagnose diseases in a microfluidic environment. Biofluid passes through the microchannel and exposed to the nanocircuit to generate a capacitance difference and diagnose any specific disease in the biofluid sample. Blood capillary flow in a microchannel curved section experience centrifugal forces that separate liquid from solid. Various blood densities and segments experience different centrifugal effects while flowing through the curved section so serum is separated from various solid matter without using external devices.
URL: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20180510&CC=US&NR=2018128823A1&KC=A1
Join the Society for Molecular Imprinting
New items RSS feed
View latest updates
Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent
e-mail alerts.
Click
here to go to the sign-up page.
Is your name
elemental or
peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay: