Abstract: Imprinting as a biological process where an animal establishes a parental relationship is called filial imprinting. However, imprinting can be implicitly inside the materials that possess suitable affinity to integrate themselves with the surrounding liquid environment. In this paper, we demonstrated an example of imprinting in MoS2 nanosheets. The as-prepared MoS2 containing polar edge and low-polar plane faces on its flower-like morphology render itself with imprinting ability to respectively adhere to water and n-hexane. Therefore, imprinted MoS2 tends to retain in the phase of imprinting solvent, which is called as solvent identification. More interestingly, imprinted MoS2 can in addition fulfill a high-efficient heterophasic extraction of rhodamine B (RhB) from water to n-hexane or lauric acid (LA) from n-hexane to water in seconds. Meanwhile, imprinted MoS2 can present self-separation after shaking by solvent identification, which avoids tedious centrifugation and filtration in separation-purification process and make it more convenient