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Reference type: Journal
Authors: Komiyama M, Mori T, Ariga K
Article Title: Molecular Imprinting: Materials Nanoarchitectonics with Molecular Information.
Publication date: 2018
Journal: Bulletin of the Chemical Society of Japan
DOI: 10.1246/bcsj.20180084
Alternative URL: http://www.journal.csj.jp/doi/abs/10.1246/bcsj.20180084

Abstract: Combining nanotechnology with the other science disciplines is necessary to produce various materials with nanoscale structural and functional information, which is nanoarchitectonics as a novel paradigm to create useful materials. One of the basic ideas in the nanoarchitectonics concept is use of molecular-level information to architect functional materials. This kind of strategy is indeed used in some pre-existing science fields and technical methods. For example, molecular imprinting technique provides functional materials possessing molecular information in insides of fabricated materials. Revisiting such known concept with the nanoarchitectonics concept would have great meaning in unification of individual research disciplines into one key concept. In this review, we survey fundamentals and recent trends of the molecular imprinting approaches upon consideration with the nanoarchitectonics. Here, aspects and examples of molecular imprinting are surveyed from fundamentals to advanced applications: (i) fundamental preparation of molecular imprinting polymers in shapes of nanoparticles, nanofibers, thin films, and monolayers; (ii) surface coverage, post-modifications, and introduction of new functional groups; (iii) imprinted materials with controllable guest bindings by external stimuli such as photo-responsive, temperature-sensitive, pH-sensitive, solvent-dependent, and multi-stimuli responsive materials; (iv) imprinting using proteins as template and protein stamping; (v) use of cyclodextrins as functional monomers; (vi) advanced functions including highly sensitive and selective sensors combined with DNA aptamers and enzymatic reactions, post-imprinting for sophisticated sensors, applications to drug delivery systems


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