Abstract: This article presents an original work aiming at rationally designing a molecularly imprinted polymer (MIP) towards high selective recognition. Assembled with (S)-naproxen as a template and 4-vinylpyridine as a functional monomer, a certain amount of cobalt, as pivot, is added for the preparation of MIP. The result indicates that the use of pivot plays obviously a positive role in increasing the specificity of MIP, so as to adsorb more for the template and less for its enantiomer. Related information indicates that this, in logic, can be a result of increasing match between binding sites and the templates, which makes the polymer capable of selectively recognizing the imprint species
Template and target information: (S)-naproxen
Author keywords: adsorption, assembled pivot, metal, molecularly imprinted polymer, selectivity