Abstract: In this work, molecularly imprinted polymer membrane (D-arginine (Arg) imprinted terpolymer P(AN-co-AA-co-AAm) membrane) was prepared by the wet phase inversion method. Acrylamide (AAm) and acrylic acid (AA) were used as the functional monomers and acrylonitrile (AN) was used as a cross linker. The removal of template molecules from the membrane matrix increased the number of free -COOH groups and reduced dimerized -COOH groups, which is an indirect evidence of the formation of recognition sites. Optical resolution was performed in ultrafiltration cell using aqueous solutions of racemic mixtures of α-amino acids (arginine and asparagine). The imprinted membrane permeated D-enantiomers preferentially achieving 93% and 72% enantiomeric excess for D-arginine and D-asparagine respectively
Author keywords: molecularly imprinted membrane, amino acids, Enantiomeric separation, Wet phase inversion method, Ultrafiltration