Abstract: Three-dimensionally ordered macroporous molecularly imprinted polymers (MMIPs) were prepared by a combination of colloidal crystal template method and molecular imprinting technique. The traditional bulk molecularly imprinted polymers (BMIPs) were simultaneously synthesized with the same recipe as the MMIPs by using methacrylic acid as functional monomer, ethylene glycol dimethacrylate as cross-linker and chloroform as porogen. SEM and BET measurements show that MMIPs have more regular macroporous structure, narrower macropore distribution, higher surface area and porosity compared with BMIPs. The isothermal and kinetic data of both polymers can be fitted with Freundlich model and pseudo-second order equation, respectively. Their specificities to the template molecules are also similar. However, the binding capability, adsorption rate coefficient and internal effective diffusion coefficient of the MMIPs are higher than BMIPs when the particle size is above 54 μm
Author keywords: cinchonine, Molecular imprinting, Polymer, ordered macropore, colloidal crystal template