MIPs logo MIPdatabase     MIP2018 Conference website
Reference type: Journal
Authors: Tang PP, Zhang HP, Huo JC, Lin XY
Article Title: Electrochemical sensor based on iron (II, III)@graphene oxide@molecularly imprinted polymer nanoparticles for interleukin-8 detection in saliva.
Publication date: 2015
Journal: Analytical Methods
DOI: 10.1039/C5AY01361E

Abstract: A novel electrochemical sensor for interleukin-8 (IL-8) detection based on Fe3O4@ graphene oxide (GO) @ molecularly imprinted polymer (MIP) nanoparticles was constructed. IL-8 was surface imprinted on the GO modified super-paramagnetic Fe3O4 nanoparticles and the synthesized Fe3O4@GO@MIP nanoparticles were self assembled onto the Au film electrode under magnetic field. Scanning electron microscopy-energy dispersive X-ray was used to characterize the core-shell structure of the nanoparticles. Cyclic voltammetry measurement was used to monitor the electrochemical process and its optimization, which illustrated that IL-8 could selectively bind to the Fe3O4@GO@MIP nanoparticle based sensor and cause a decrease of the measured current (the higher concentration of IL-8, the larger decrease of the current). The results revealed that the sensor displayed superb resistance to non-specific binding, very attractive detection limit as low as 0.04 pM, and a wide linear range from 0.1 to 10 pM towards IL-8. Furthermore, the sensor was also successfully used for the detection of IL-8 in saliva. Therefore, the Fe3O4@GO@MIP nanoparticle based sensor might provide a sensitive, rapid, selective and cost-effective method for IL-8 determination and related cancer marker analysis


  Mister Benzene Drinkies frosty mug  Chemistry peptide mug  Beach bunny periodic table shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon