MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Lei Y, Xu GH, Wei FD, Yang J, Hu Q
Article Title: Preparation of a stir bar coated with molecularly imprinted polymer and its application in analysis of dopamine in urine.
Publication date: 2014
Journal: Journal of Pharmaceutical and Biomedical Analysis
Volume: 94
Page numbers: 118-124.
DOI: 10.1016/j.jpba.2014.01.041
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0731708514000788

Abstract: A molecularly imprinted polymer coated stir bar (MIP-SB) using dopamine as a template was fabricated. The adsorptive capacity of the MIP-SB was almost 4 times over that of non-imprinted stir bar. The MIP-SB showed good extracting selectivity for dopamine when used to adsorb dopamine and its analogs. An analytical method to determine dopamine in urine sample was established by combining MIP-SB sorptive extraction with HPLC-fluorescence detector. The linear range of dopamine concentration was 0.378-18.9 ng/ml with correlation coefficient of 0.9990, and the limit of quantification was about 0.0945 ng/ml (S/N = 10). The recoveries of dopamine with spiked urine samples at three different levels were between 92.3 and 106.9%, and the relative standard deviations were within 13.2% (n = 3). The method is simple and suitable for the determination of dopamine in human urine for clinical application
Template and target information: dopamine
Author keywords: molecularly imprinted polymer, Stir bar sorptive extraction, dopamine, human urine

  Eat, sleep, imprint, repeat greetings card  SMI logo mug  Man of proper-tea mug in blue

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner