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Reference type: Journal
Authors: Meador DS, Spivak DA
Article Title: Absolute Configuration Determination Using Enantiomeric Pairs of Molecularly Imprinted Polymers.
Publication date: 2014
Journal: Organic Letters
Volume: 16
Issue: (5)
Page numbers: 1402-1405.
DOI: 10.1021/ol500173y

Abstract: A new method for determination of absolute configuration (AC) is demonstrated using an enantiomeric pair of molecularly imprinted polymers, referred to as "DuoMIPs". The ratio of HPLC capacity factors (k') for the analyte on each of the DuoMIPs is defined as the γ factor and can be used to determine AC when above 1.2. A mnemonic based on the complementary binding geometry of the DuoMIPs was used to aid in understanding and prediction of AC
Template and target information: Boc-tyrosine

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