MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Yan HY, Wang MY, Han YH, Qiao FX, Row KY
Article Title: Hybrid molecularly imprinted polymers synthesized with 3-aminopropyltriethoxysilane-methacrylic acid monomer for miniaturized solid-phase extraction: A new and economical sample preparation strategy for determination of acyclovir in urine.
Publication date: 2014
Journal: Journal of Chromatography A
Volume: 1346
Page numbers: 16-24.
DOI: 10.1016/j.chroma.2014.04.045
Alternative URL: http://www.sciencedirect.com/science/article/pii/S002196731400613X

Abstract: The miniaturized molecularly imprinted solid-phase extraction (mini-MISPE) coupled with high-performance liquid chromatography was proposed for the determination of acyclovir in urine. 1.5-mL tapered plastic centrifuge tube filled with hybrid molecularly imprinted polymers (HMIPs) was used as the cartridge of mini-MISPE, and the HMIPs synthesized with 3-aminopropyltriethoxy silane-methacrylic acid as monomer exhibited good recognition and selectivity for acyclovir. Under the optimized condition, good linear calibration was obtained in a range of 0.5-15 μg mL-1 with the correlation coefficient of 0.9994, and the recoveries at three spiked levels were 91.6-103.3% in urine with the relative standard deviation (RSD) of £3.5%. Excellent intra-day and inter-day repeatability were achieved with RSD of £2.6% and 4.0% in three different concentrations. This method combined the advantages of HMIPs and mini-MISPE, and it could become an alternative tool for analyzing the residues of acyclovir in complex urine matrices
Template and target information: acyclovir
Author keywords: Hybrid molecularly imprinted polymers, 3-Aminopropyltriethoxysilane-methacrylic acid monomer, Miniaturized molecularly imprinted solid-phase extraction, Acyclovir, urine


  Live and Let MIP spoof movie poster customisable greetings card  Chemistry peptide mug  Chemists are fun customisable shirt






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner