MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Betatache A, Lagarde F, Sanglar C, Bonhomme A, Leonard D, Jaffrezic-Renault N
Article Title: Gold Electrodes Modified with Molecular Imprinted Acrylate Polymer for Impedimetric Determination of Testosterone.
Publication date: 2014
Journal: Sensors and Transducers
Volume: 27
Issue: (Special Issue May 2014)
Page numbers: 92-99.
Alternative URL: http://www.sensorsportal.com/HTML/DIGEST/may_2014/Special_issue/P_SI_483.pdf

Abstract: A moleculary imprinted polymer (MIP) sensor was developed for impedimetric detection of testosterone. 4,4'-azobis(4-cyanovaleric acid) initiator was first grafted onto a gold electrode modified by a selfassembled monolayer of thiolamine (11-amino-1-undecanethiol). Methacrylic acid and ethylene glycol dimethacrylate were prepolymerized by photo-polymerization in presence of testosterone as template and then spincoated and polymerized on the functionalized electrode surface. The different steps of MIP sensor fabrication were controlled using electrochemical impedance spectroscopy (EIS), Fourier transform infrared spectroscopy and time of flight-secondary ion mass spectrometry. After template removal, the biosensor response, expressed as the variation of charge transfer resistance at the electrode/electrolyte interface measured by EIS, increased linearly with testosterone concentration up to 50 μg L-1. The sensitivity was 0.28 per log C for testosterone, while it was only 0.0085 and 0.020 for methyltestosterone and 17β-estradiol, respectively. A very good limit of detection (103 ng L-1) was achieved for testosterone. The sensitivity of the non imprinted polymer sensor, prepared the same way but in absence of template, was 18 times lower than that obtained with the MIP. Copyright 2014 IFSA Publishing, S. L.
Template and target information: testosterone
Author keywords: Moleculary imprinted polymer, testosterone, electrochemical impedance spectroscopy, cyclic voltammetry, TOF-SIMS, FTIR

  Periodic table Stew - the chemical formula for stew shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner