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Reference type: Journal
Authors: Dai J, Zhang Y, Pan MF, Kong LJ, Wang S
Article Title: Development and Application of Quartz Crystal Microbalance Sensor Based on Novel Molecularly Imprinted Sol-Gel Polymer for Rapid Detection of Histamine in Foods.
Publication date: 2014
Journal: Journal of Agricultural and Food Chemistry
Volume: 62
Issue: (23)
Page numbers: 5269-5274.
DOI: 10.1021/jf501092u

Abstract: To rapidly detect histamine (HA) in foods, a novel material for HA-specific recognition was synthesized by a sol-gel process and coated on a quartz crystal microbalance (QCM) sensor. The Scatchard model was used to evaluate the adsorption performance of the material; high affinity for HA was demonstrated. Based on QCM frequency change, the sensor exhibited linear behavior for HA concentrations of 0.11 x 10-2 to 4.45 x 10-2 mg L-1, a detection limit of 7.49 x 10-4 mg kg-1 (S/N = 3), high selectivity for HA (selectivity coefficient >4) compared with structural analogues, good reproducibility, and long-term stability. The sensor was used to determine the concentration of HA in spiked fish products; the recovery values were satisfactory (93.2-100.4%) and compared well with those obtained by high-performance liquid chromatography (correlation coefficient, r2 = 0.9965)
Template and target information: histamine, HA
Author keywords: histamine, Quartz crystal microbalance sensor, sol-gel, molecularly imprinted polymer

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