MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Qiao L, Gan N, Hu FT, Wang D, Lan HZ, Li TH, Wang HF
Article Title: Magnetic nanospheres with a molecularly imprinted shell for the preconcentration of diethylstilbestrol.
Publication date: 2014
Journal: Microchimica Acta
Volume: 181
Issue: (11-12)
Page numbers: 1341-1351.
DOI: 10.1007/s00604-014-1257-y
Alternative URL: https://www.researchgate.net/publication/271923691_Magnetic_nanospheres_with_a_molecularly_imprinted_shell_for_the_preconcentration_of_diethylstilbestrol

Abstract: We report on the preparation of magnetic nanoparticles coated with a surface imprinted polymer for use in the preconcentration of diethylstilbestrol (DES). The magnetic molecularly imprinted nanoparticles (m-MINPs) were fabricated by first coating magnetite nanoparticles with a layer of Nafion which is polyanionic. Next, the resulting particles were coated with polydopamine (which is polycationic at near-neutral pH values) in the presence of DES as a template. The thickness of the coating containing the DES template is quite thin so that it can be removed within 18 h. The m-MINPs devoid of DES have a typical diameter of 500 nm and exhibit fast adsorption kinetics and sensitive magnetic response to a magnet. The m-MINPs can recognize DES with high specificity over many other estrogens (separation factor β >1.9) and were employed for the dispersive solid-phase extraction of DES which then was quantified by HPLC. The method was applied to determine DES in (spiked) milk powder samples. The recoveries ranged from 90.7 to 105.2 % (intra-day) and from 85.5 to 102.3 % (inter-day) at spiking levels of 10, 50, and 100 ng g-1. The linear ranges were 3.5-1,000 ng g-1 with the correlation coefficient of 0.9983. The detection limit was 0.99 ng g-1 of milk powder. The m-MINPs are reusable. After 12 adsorption-elution cycles, the recovery was still higher than 80 %
Template and target information: diethylstilbestrol, DES
Author keywords: Layer-by-layer self-assembly, Magnetic molecularly imprinted polymers, Dispersive solid-phase extraction, high performance liquid chromatography, diethylstilbestrol

  mipdatabase.com logo special offer joke shirt  Lab Hero Periodic tablemug  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner