MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Sun XL, Wang JC, Li Y, Yang JJ, Jin J, Shah SM, Chen JP
Article Title: Novel dummy molecularly imprinted polymers for matrix solid-phase dispersion extraction of eight fluoroquinolones from fish samples.
Publication date: 2014
Journal: Journal of Chromatography A
Volume: 1359
Page numbers: 1-7.
DOI: 10.1016/j.chroma.2014.07.007
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0021967314010760

Abstract: A series of novel dummy molecularly imprinted polymers (DMIPs) were prepared as highly class-selective sorbents for fluoroquinolones. A non-poisonous dummy template, daidzein, was used for the first time to create specific molecular recognition sites for fluoroquinolones in the synthesized polymers. The influence of porogen polarity on dummy molecular imprinting effect was studied. The DMIP prepared using dimethylsulfoxide-acetonitrile (1:1.8, v/v) as porogen achieved the highest imprinting factors (IF) for fluoroquinolones over a range of IF 13.4Gă˘84.0. This DMIP was then used for selective extraction of eight fluoroquinolones (fleroxacin, ofloxacin, norfloxacin, pefloxacin, ciprofloxacin, lomefloxacin, enrofloxacin and gatifloxacin) from fish samples based on dummy molecularly imprinted matrix solid-phase dispersion (DMI-MSPD). The extracted fluoroquinolones were subsequently analyzed by high-performance liquid chromatography (HPLC) equipped with a fluorescence detector (FLD). The developed method had acceptable recoveries (64.4-102.7%) and precision (RSDs: 1.7-8.5%, n = 5) for determination of fluoroquinolones in fish samples fortified at levels of 10 and 100 ng g-1. The limits of detection (LODs) for identification of eight fluoroquinolones ranged between 0.06 and 0.22 ng g-1. The results demonstrated great potential of the optimized method for sample preparation in routine analysis of trace fluoroquinolones in fish samples
Template and target information: dummy template, daidzein, fluoroquinolones, fleroxacin, ofloxacin, norfloxacin, pefloxacin, ciprofloxacin, lomefloxacin, enrofloxacin, gatifloxacin
Author keywords: Fluoroquinolones, Molecularly imprinted polymers, dummy template, Class-selective, Matrix solid-phase dispersion.

  Eat, sleep, imprint, repeat shirt  SMI logo mug  Woman of proper-tea mug in green


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner