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Reference type: Journal
Authors: Guerreiro A, Poma A, Karim K, Moczko E, Takarada J, de Vargas-Sansalvador IP, Turner N, Piletska E, de Magalh„es CS, Glazova N, Serkova A, Omelianova A, Piletsky S
Article Title: Influence of Surface-Imprinted Nanoparticles on Trypsin Activity.
Publication date: 2014
Journal: Advanced Healthcare Materials
Volume: 3
Issue: (9)
Page numbers: 1426-1429.
DOI: 10.1002/adhm.201300634

Abstract: Here, the modulation of enzyme activity is presented by protein-imprinted nanoparticles produced using a solid-phase approach. Using trypsin as target, binding of the nanoparticles to the enzyme results in its inhibition or in stabilization, depending on the orientation of the immobilized enzyme used during imprinting
Template and target information: trypsin, protein, enzyme
Author keywords: enzyme inhibition, Molecularly imprinted polymers, molecular recognition, nanoparticles, supramolecular chemistry


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