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Abstract: One molecule of zinc ion (Zn2+) could combine with two molecules of sulfadiazine (SDZ) to form a complex. Based on this concept, two experiments were performed to improve the preparation of sulfadiazine molecularly imprinted polymer materials (MIPs). One experiment used the complex of SDZ-Zn as template to replace SDZ in order to synthesize MIPs, which displayed higher selectivity and imprint factor. The second experiment used a methanol-acetic acid solution (9 : 1, v/v) containing 0.02 mol L-1 Zn2+ as the eluate to remove the template molecules from the synthesized MIPs, which could rapidly remove the template at 80 °C within two hours. Compared with the traditional Soxhlet extraction, the time was largely shortened
Template and target information: sulfadiazine, SDZ, sulfadiazine-Zn(II) complex