MIPs logo MIPdatabase     MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: He HL, Li H, Gao YK, Chen D, Shi LY, Peng J, Du SH, Chen LN
Article Title: A Novel Molecularly Imprinted Polymer for the Solid-Phase Extraction of Tanshinones from Serum.
Publication date: 2015
Journal: Analytical Letters
Volume: 48
Issue: (1)
Page numbers: 47-60.
DOI: 10.1080/00032719.2014.930865

Abstract: A molecularly imprinted polymer (MIP) was synthesized by precipitation polymerization with tanshinone IIA as the template and used as an adsorbent for solid-phase extraction (SPE). A simulation was employed to predict the most suitable polymerization solvent, the functional monomer, and the molar ratio of template to monomer. The obtained imprinted materials were evaluated by transmission electron microscopy, scanning electron microscopy, rebinding experiments, exhibiting good morphology, and high binding to tanshinone IIA. Compared with nonimprinted polymers, the imprinted material exhibited a higher sorption capacity, up to 34.09 μmol g-1, and better selectivity for tanshinone IIA and its structural analogs. The imprinted polymer was successfully employed for SPE coupled with high-performance liquid chromatography for the determination of tanshinone IIA, cryptotanshinone, and tanshinone I in fortified serum. The mean recoveries were between 91.5% and 95.1% with relative standard deviations less than 4.9%. These results demonstrate a highly selective isolation and determination of tanshinones
Template and target information: tanshinone IIA, cryptotanshinone, tanshinone I
Author keywords: high-performance liquid chromatography, molecularly imprinted polymer, precipitation polymerization, Solid-phase extraction, Tanshinone IIA


  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon