MIPs logo MIPdatabase     MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Tadi KK, Motghare RV, Ganesh V
Article Title: Electrochemical Detection of Sulfanilamide Using Pencil Graphite Electrode Based on Molecular Imprinting Technology.
Publication date: 2014
Journal: Electroanalysis
Volume: 26
Issue: (11)
Page numbers: 2328-2336.
DOI: 10.1002/elan.201400251

Abstract: Molecularly imprinted polymer (MIP) for sulfanilamide (SN) sensing is prepared through in-situ electropolymerization of pyrrole (Py) on pencil graphite electrode (PGE). Computational study using density functional theory with B3LYP level is performed to analyze and evaluate the template-monomer geometry. Among the various functional monomers studied pyrrole is found to have the highest binding interaction energy with SN and it is chosen as a functional monomer. Electropolymerization of pyrrole in the presence of SN on PGE is carried out using cyclic voltammetry. Structural morphology of the imprinted polymer is characterized by field emission scanning electron microscopy (FESEM) studies. Quantitative measurements of MIP based SN detection are performed by using cyclic voltammetry and differential pulse voltammetry studies. Several important kinetic parameters influencing the performance of SN sensor such as limit of detection, linear concentration range and sensitivity etc. are determined and analyzed. Under the optimized conditions, MIP based SN sensor proposed in this work has a very low detection limit of 2.0 x 10-8 M (S/N=3) and possesses two linear ranges from 5.0 x 10-8 to 1.1 x 10-6 M and 1.1 x 10-6 to 48 x 10-6 M with a sensitivity value of 1.158 and 0.012 μA/μM respectively. This particular sensor shows a good selectivity towards SN in presence of potential other structural analogue interferences namely sulfamethaxazole, sulfathiazole and sulfadiazine. Furthermore, the fabricated sensor is successfully applied to quantitatively determine and analyze SN present in spiked human serum and ground water samples
Template and target information: sulfanilamide, SN
Author keywords: Computational chemistry, differential pulse voltammetry, electrochemical sensors, electropolymerization, molecularly imprinted polymer, Pencil graphite electrode, polypyrrole, Sulfanilamide


  I love MIPs magnet  multi MIPs logo mug  American periodic table patriotic shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon