MIPs logo MIPdatabase    HoHoHo MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Hu YX, Feng SL, Gao F, Li-Chan ECY, Grant E, Lu XN
Article Title: Detection of melamine in milk using molecularly imprinted polymers-surface enhanced Raman spectroscopy.
Publication date: 2015
Journal: Food Chemistry
Volume: 176
Page numbers: 123-129.
DOI: 10.1016/j.foodchem.2014.12.051
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0308814614019645

Abstract: A novel biosensor combining molecularly imprinted polymers and surface-enhanced Raman spectroscopy (MIPs-SERS) determines melamine in whole milk. MIPs were synthesized by bulk polymerization of melamine (template), methacrylic acid (functional monomer), ethylene glycol dimethacrylate (cross-linking agent) and 2,2'-azobisisobutyronitrile (initiator). Static and kinetic adsorption tests validated the use of MIPs to efficiently separate and enrich melamine from whole milk. Silver dendrite nanostructure served as SERS-active substrate for signal collection. Principal component analysis and hierarchical cluster analysis segregated Raman signatures of whole milk samples with different melamine concentrations. Regression models showed a good linear relationship (R2 = 0.93) between the height of melamine SERS band (at 703 cm-1) and melamine concentration in the range from 0.005 mmol L-1 to 0.05 mmol L-1. The limit of detection and limit of quantification were 0.012 mmol L-1 and 0.039 mmol L-1, confirming the high sensitivity of this biosensor to accurately determine melamine in whole milk. Simple sample pretreatment reduced full analysis time to determine melamine in whole milk to less than 20 min
Template and target information: melamine
Author keywords: Molecularly imprinted polymers, SERS, Raman spectroscopy, Melamine, Food adulteration, chemometrics


  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon