MIPs logo MIPdatabase     MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Naeimi H, Nejadshafiee V, Masoum S
Article Title: Highly efficient copper-imprinted functionalized mesoporous organosilica nanocomposites as a recyclable catalyst for click synthesis of 1,2,3-triazole derivatives under ultrasound irradiation: multivariate study by factorial design of experiments.
Publication date: 2015
Journal: RSC Advances
Volume: 5
Issue: (20)
Page numbers: 15006-15016.
DOI: 10.1039/C4RA17229A

Abstract: We have developed a convenient green method for one-pot synthesis of β-hydroxy-1,2,3-triazoles through three-component coupling of a variety of epoxides and alkynes over copper-imprinted periodic mesoporous organosilica nanocomposites (Cu@PMO NCs) in water under ultrasound irradiation. The surface response obtained from an experimental Box-Behnken design (BBD) was used to model the catalytic synthesis of β-hydroxy-1,2,3-triazole. This method was an economical way of obtaining the optimal reaction conditions based on a restricted number of experiments. Reactions were performed in ultrasound equipment and different variables, such as the amount of catalyst, ultrasound irradiation frequency and ultrasound time, were investigated. Our method is more environmentally friendly than previous methods because it uses water as the solvent, uses ultrasound irradiation, uses a catalyst that is reusable for up to six runs without appreciable loss of activity, and has short reaction times and high yields. Furthermore, the mathematical model of the reaction represents the process well and shows good correlation with the experimental results
Template and target information: copper ion


  Periodic table Teacher shirt  Science peptide mug    mug featuring the element Copper

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon