MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Bates F, del Valle M
Article Title: Voltammetric sensor for theophylline using sol-gel immobilized molecularly imprinted polymer particles.
Publication date: 2015
Journal: Microchimica Acta
Volume: 182
Issue: (5-6)
Page numbers: 933-942.
DOI: 10.1007/s00604-014-1413-4

Abstract: Sensors incorporating molecularly imprinted polymers (MIPs) are feasible in concept though the reproducibility of such devices can be compromised by the large number of interdependent steps. For this reason, many researchers have focused on the synthesis of MIP particles only, not on their immobilization. Herein is presented a sol-gel based method for immobilization of unmodified MIP particles for use in an electrochemical sensor. The macroporous particles were prepared using precipitation-polymerization and imprinted with theophylline. The sol-gel was combined with graphite microparticles (50 μm) and the composite was deposited on the surfaced of an epoxy-graphite electrode. The sensor was then tested for its response to theophylline using differential pulse voltammetry. A limit of detection of 1 μM was observed and a relative standard deviation of 6.85 %. The electrode can be regenerated via a thermal washing process which was accompanied by an initial signal loss of 29.3 %. Any further regeneration caused a signal loss of 2.4 % only
Template and target information: theophylline
Author keywords: molecularly imprinted polymers (MIP), sol-gel, Graphite, theophylline, differential pulse voltammetry


  SMI logo tie  Mug featuring the name Ferdia spelled out in the single letter amino acid code    Mug featuring the template Theophylline






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner