MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Li J, Hu XL, Guan P, Zhang XY, Qian LW, Song RY, Du CB, Wang CL
Article Title: Preparation of molecularly imprinted polymers using ion-pair dummy template imprinting and polymerizable ionic liquids.
Publication date: 2015
Journal: RSC Advances
Volume: 5
Issue: (77)
Page numbers: 62697-62705.
DOI: 10.1039/C5RA10455F

Abstract: Ionic liquid based molecularly imprinted polymers have attracted considerable attention as biomimetic recognition materials due to their water-compatibility and high binding capacities. However, the selective recognition was unsatisfactory. In order to overcome this defect, we developed a novel dummy template ionic liquid based molecularly imprinted polymer, which used 1-butyl-3-vinylimidazolium α-aminohydrocinnamic acid salt as a functional monomer and the dummy template. Binding experiments showed that the obtained molecularly imprinted polymer possesses a high binding capacity (280.18 μmol g-1), imprinting factor (3.17) and selectivity factor (5.75). Molecular simulation results demonstrated that the high selectivity is attributed to the formation of ion-pairs between imidazolium and l-phenylalanine, which could be located in the imprinted cavities to improve the imprinted material's efficiency. Subsequently, the dummy template ionic liquid based imprinted polymer was employed as packing in a solid phase extraction cartridge to analyze the l-phenylalanine in the blood of a phenylketonuria patient. The results indicated that the obtained dummy template ionic liquid based imprinted polymer has good analytical performance. Thus, the dummy imprinting combined with the ionic liquid is a useful way to improve the specific recognition of ionic liquid based molecular imprinted polymers, so that this method offers promising new applications in the field of the analysis of biological samples
Template and target information: dummy template, α-aminohydrocinnamic acid salt, l-phenylalanine, Phe, L-Phe

  I love MISPE shirt  multi MIPs logo mug  British periodic table patriotic tote bag


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner