MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Duan HM, Li LL, Wang XJ, Wang YH, Li JB, Luo CN
Article Title: β-Cyclodextrin/chitosan-magnetic graphene oxide-surface molecularly imprinted polymer nanocomplex coupled with chemiluminescence biosensing of bovine serum albumin.
Publication date: 2015
Journal: RSC Advances
Volume: 5
Issue: (84)
Page numbers: 68397-68403.
DOI: 10.1039/C5RA11061K

Abstract: In this report, a sensitive and selective chemiluminescence (CL) biosensor for bovine serum albumin (BSA) coupled with a surface molecularly imprinted polymer nanocomplex using β-cyclodextrin/chitosan-magnetic graphene oxide as backbone material (β-CD/Cs-MGO-SMIP) was investigated. The material β-CD/Cs-MGO combined with β-cyclodextrin, chitosan and graphene oxide was used to provide multiple imprinting sites and a large surface area was characterized by SEM, XRD and FTIR. It was found that β-CD/Cs-MGO-SMIP followed the Langmuir isotherm equation and pseudo-second order sorption kinetics when binding the template. This material demonstrated fast mass transfer, a promoted rate of removal of the biomacromolecule and excellent recognition and adsorption ability for the imprinting cavities situated at the surface of β-CD/Cs-MGO, which enabled easy access to BSA. Subsequently, a highly sensitive CL biosensor for BSA was proposed based on the strong recognition effect between β-CD/Cs-MGO-SMIP and BSA which led to a high selectivity of the sensor, and the proposed biosensor could assay in the range 5.0 x 10-7 to 1.0 x 10-4 mg mL-1 with a detection limit of 1.1 x 10-7 mg mL-1. The obtained recoveries were between 94% and 106% when determining samples
Template and target information: protein, bovine serum albumin, BSA


  Periodic table Coach hat  PhD Scientist peptide mug  Gravity waves shirt






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner