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Authors: Ji WH, Xie HK, Zhou J, Wang X, Ma XL, Huang LQ
Article Title: Water-compatible molecularly imprinted polymers for selective solid phase extraction of dencichine from the aqueous extract of Panax notoginseng.
Publication date: 2016
Journal: Journal of Chromatography B
Volume: 1008
Page numbers: 225-233.
DOI: 10.1016/j.jchromb.2015.11.053
Alternative URL: http://www.sciencedirect.com/science/article/pii/S1570023215303226
Abstract: Specific molecularly imprinted polymers for dencichine were developed for the first time in this study by the bulk polymerization using phenylpyruvic acid and dl-tyrosine as multi-templates. The photographs confirmed that molecularly imprinted polymers prepared using N,N'-methylene diacrylamide as cross-linker and glycol dimethyl ether as porogen displayed excellent hydrophilicity. Selectivity, adsorption isotherm and adsorption kinetics were investigated. The sample loading-washing-eluting solvent was optimized to evaluate the property of molecularly imprinted solid phase extract. Compared with LC/WCX-SPE, water-compatible molecularly imprinted solid phase extraction displayed more excellent specific adsorption performance. The extracted dencichine from Panax notoginseng with the purity of 98.5% and the average recovery of 85.6% (n = 3) was obtained
Template and target information: dencichine
Author keywords: Molecularly imprinted polymers, HPLC, natural products, Dencichine, Panax notoginseng
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