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Reference type: Journal
Authors: Hegazy EA, Sabry GM, Ezz MK, Kamal H, Lotfy S, Mansour SZ, Eissa DH
Article Title: Radiation Synthesis and Characterization of Cholesterol Molecularly Imprinted Polymer of Crosslinked Hydroxyethyl Methacrylate.
Publication date: 2016
Journal: International Journal of Science and Research (IJSR)
Volume: 5
Issue: (1)
Page numbers: ArticleID:NOV152733.
Alternative URL: http://www.ijsr.net/archive/v5i1/NOV152733.pdf

Abstract: Cholesterol-imprinted poly hydroxyethyl methacrylate (MIP) andnon-imprinted polyhydroxyethyl methacrylate (NIP) have been prepared via polymerization by gamma radiation. The functional structure of the imprinted and non-imprinted polymers were characterized by Fourier Transform Infrared spectroscopy (FT-IR); the spectrum showed that the HEMA interacts with cholesterol through H-bonds. The surface morphology of NIP and MIP were investigated by scanning electron microscope (SEM) and the MIP image appeared as a rough surface, while NIP had no pores. The specificity of MIP to interact with the print molecular was studied cholesterol and the results showed a higher cholesterol adsorption by MIP than that by NIP. This work approachesto design robust MIP to mimic natural recognition entities as adsorbed materials of cholesterol.
Template and target information: cholesterol
Author keywords: molecular imprinted polymers, NIP, HEMA, cholesterol, gamma radiation

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