MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Wang JF, Zhou LM, Liu XL, Wang QH, Zhu DQ
Article Title: Tribasic cross-linker molecular imprinted chiral stationary phase.
Publication date: 2000
Journal: Chinese Journal of Analytical Chemistry
Volume: 28
Issue: (10)
Page numbers: 1224-1228.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-FXHX200010007.htm

Abstract: Molecular imprinted polymers against N-Cbz-L-Trp utilizing 2-VP + AM as combined functional monomer and trimethylolpropane trimethacrylate (TRIM) as tribasic cross-linker were prepared and evaluated in HPLC mode. Comparing with molecular imprinted polymer (MIP) utilizing ethylene glycoldimethacrylate (EDMA) as cross-linker, it was found that MIP utilizing TRIM as cross- linker showed higher cross-link intensity and baseline chiral separation of the template enantiomer was achieved on a shorter column. More functional monomers were used and more template molecules were imprinted in the MIP utilizing TRIM as cross- linker. This could result in more recognition cavities in the polymer and the number of the imprinted cavities in unit weight of chiral stationary phase was greater. So the capacity factor was increased and column capacity was high enough for preparation separation. Meanwhile, the higher specific recognition ability of the imprinted cavities to the imprinted molecule and enantiomers alike leads to the higher chiral cross-selectivity because of more ordered arrangement of the tribasic cross-linked MIP
Template and target information: N-Cbz-L-Trp

  Template of Doom spoof movie poster customisable greetings card  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner