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Reference type: Journal
Authors: Watabe Y, Kondo T, Morita M, Tanaka N, Haginaka J, Hosoya K
Article Title: Determination of bisphenol A in environmental water at ultra-low level by high-performance liquid chromatography with an effective on-line pretreatment device.
Publication date: 2004
Journal: Journal of Chromatography A
Volume: 1032
Issue: (1-2)
Page numbers: 45-49.
DOI: 10.1016/j.chroma.2003.11.079

Abstract: We have developed a simple HPLC method for the microanalysis of bisphenol A (BPA), which is often contained in environmental water and is known as an endocrine disrupter. HPLC coupled with electrochemical detection requires a simpler procedure of pretreatment compared to GC-MS. In this study, we analyzed BPA using molecularly imprinted polymer as an on-line pretreatment device. This polymer has molecular recognition sites and provides specific selectivity in extraction process. Due to this effect, the detection limit obtained with this HPLC was 0.36 ng/l. This method applied to environmental water and purified water samples containing 2-70 ng/l of BPA successfully. Furthermore, UV detection was performed in some actual analyses. (C) 2004 Elsevier B.V. All rights reserved

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