MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Busi E, Basosi R, Ponticelli F, Olivucci M
Article Title: An innovative approach to the design of plastic antibodies: molecular imprinting via a non-polar transition state analogue.
Publication date: 2004
Journal: Journal of Molecular Catalysis A: Chemical
Volume: 217
Issue: (1-2)
Page numbers: 31-36.
DOI: 10.1016/j.molcata.2004.03.044

Abstract: An acrylic resin imprinted with a transition state analogue which possesses a dominant non-polar structure was synthesized. As a model for this study the Diels-Alder reaction was chosen since, it is well-known and possesses a stable and synthetically achievable transition state analogue. It is shown that the plastic antibody synthesized in this study catalyzes the Diels-Alder reaction with an efficiency comparable to that of a recently developed monoclonal catalytic antibody. In fact the Lineweaver-Burk V-max observed for the two catalysts appears to be of the same order of magnitude. We argue that plastic antibodies can be successfully used to catalyze reactions with a transition state of low polarity. Moreover, they appear to represent a more flexible catalyst when varied reaction conditions and solvent environments are needed. (C) 2004 Elsevier B.V. All rights reserved

  Eat, sleep, imprint, greetings card  SMI logo mug  Man of proper-tea mug in green

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner