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Reference type: Journal
Authors: Davis RW, DiCesare JC
Article Title: Synthesis of molecularly imprinted polymers using combinatorial chemistry.
Publication date: 2001
Journal: Abstracts of Papers of the American Chemical Society
Volume: 221
Issue: (CHED)
Page numbers: 671.

Abstract: The major focus of this research is to design molecularly imprinted polymer (MIP) films that are able to selectively concentrate and bind a specific chemical warfare agent. The combination of combinatorial chemistry and sol-gel processing will allow fabrication parameters to be quickly and efficiently optimized. The nerve agents are divided into two categories, non-persistent (Soman and Sarin) and persistent (VX). Non-persistent agents will use their hydrolysis product as a template for preparing the MIP. Persistent agents will use a new class of simulants based on the carbamate and carbonate functional group. These new functional group simulants are bio-isosteric to the phosphonate group found in V)( and therefore should provide an appropriate template


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