Book title: Biochemical Technology Part B
Editors: Bittar EE, Danielsson B, Bulow L
Series title: Advances in Molecular and Cell Biology
Volume number: 15B
Abstract: Various attempts to produce specific binding sites in synthetic polymers analogous to those of biological receptors or natural enzymes are described here. To this end, an imprinting procedure was used with the aid of templates in cross-linked polymers. Suitable polymerizable binding groups were bound to a template molecule. This complex was copolymerized into highly cross-linked polymers. After the removal of the templates the remaining cavities possessed a shape and arrangement of their functional groups corresponding to that of the template. New developments in the application of this technique and experiments towards the understanding of the mechanism of the molecular recognition are discussed in detail.