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Reference type: Journal
Authors: Schwarz L, Bowyer MC, Holdsworth CI, McCluskey A
Article Title: Synthesis and evaluation of a molecularly imprinted polymer selective to 2,4,6-trichloroanisole.
Publication date: 2006
Journal: Australian Journal of Chemistry
Volume: 59
Issue: (2)
Page numbers: 129-134.
DOI: 10.1071/CH05318

Abstract: In the wine industry 2,4,6-trichloroanisole (TCA) has been identified as the primary contaminant responsible for 'cork taint'. A molecularly imprinted polymer (MIP) selective for TCA was prepared in three porogens (hexane, acetonitrile, and dichloromethane) of varying polarities using non-covalent molecular imprinting techniques. Target rebinding to the MIP was found to be most effective in its porogenic solvent and highest in dichloromethane (imprinting factor=3.65). Competitive binding assays performed against a range of close structural analogues demonstrated a preference for the target molecule
Template and target information: 2,4,6-trichloroanisole, TCA

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