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Abstract: Design and preparation of synthetic polymers bearing bio-functions, i.e., artificial receptors, have been significant subjects for understanding the molecular recognition phenomena in biological systems and for developing novel biomimetic materials. Molecular imprinting has been recognized as a technique to construct receptor structures within synthetic polymer networks. In this template polymerization technique, the pre-arrangement of binding sites is achieved by either covalent bonding or non-covalent interactions between a molecule to be recognized (template) and polymerizable monomers with functional groups (functional monomer) capable of the complex formation with the template. After the polymerization around the template-functional monomer complexes, the template is removed from the polymer, resulting in the formation of complementary binding sites for the template. This presentation is describing design strategies and potential applications of molecularly imprinted receptors, employing model analytical targets of biological importance