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Reference type: Journal
Authors: Zhang FJ, Cheng GX, Ying XG
Article Title: Emulsion and macromolecules templated alginate based polymer microspheres.
Publication date: 2006
Journal: Reactive and Functional Polymers
Volume: 66
Issue: (7)
Page numbers: 712-719.
DOI: 10.1016/j.reactfunctpolym.2005.10.022
Alternative URL: http://www.sciencedirect.com/science/article/B6TY0-4HVDJGD-1/2/c893aa91d11bf339a15ec0637a3d183b

Abstract: With the aim of improving the performance of calcium alginate (Ca-Alg) hydrogel, a small quantity (5% of dry mass of sodium alginate) of hydroxyethyl cellulose (HEC) was used to associate sodium alginate to form interpenetrating networks (IPNs). Swelling results and mechanical stability tests showed that the formation of IPNs considerably restrained dried samples from swelling in 0.9% sodium chloride aqueous solution and reinforced the mechanical strength of microspheres. For emulsion droplets as template, microscopy showed that the original emulsion templating method employed in preparation of macroporous Ca-Alg microspheres was also applicable in the IPNs system. As for bovine serum albumin molecules as template, Alg/HEC microspheres showed a better recognition effect than that of Ca-Alg microspheres. The reduced network mesh size and strengthened cross-linkages in IPNs are responsible for these results
Template and target information: protein, bovine serum albumin, BSA
Author keywords: alginate, IPNs, template, imprinting, microsphere


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