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Reference type: Journal
Authors: Schrader T, Koch S
Article Title: Artificial protein sensors.
Publication date: 2007
Journal: Molecular BioSystems
Volume: 3
Issue: (4)
Page numbers: 241-248.
DOI: 10.1039/b614103j

Abstract: Protein recognition by synthetic molecules is a challenging endeavour, since these materials must bind to a large relatively flat surface domain and recognize a unique distribution of amino acid residues of varying charge, size and shape. The most promising routes involve specific metal coordination, epitope-docking on miniature proteins, aptamer selection, nonnatural peptide isosteres, functionalized platforms, secondary structure mimetics, molecular imprinting and receptors embedded in lipid layers.
Template and target information: Review - artificial protein sensors


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