MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Ouyang RZ, Lei JP, Ju HX, Xue YD
Article Title: A Molecularly Imprinted Copolymer Designed for Enantioselective Recognition of Glutamic Acid.
Publication date: 2007
Journal: Advanced Functional Materials
Volume: 17
Issue: (16)
Page numbers: 3223-3230.
DOI: 10.1002/adfm.200700143
Alternative URL: http://www.chem-ju-nju-edu.com/lunwenlunzhu/paper2007/246%20AFM%20Ouyang.pdf

Abstract: A newly designed molecularly imprinted polymer (MIP) material was developed and successfully used as recognition element to fabricate a capacitive sensor for enantioselective recognition of glutamic acid (Glu). The MIP with a well-defined structure was synthesized on a gold electrode in one step by electrochemical copolymerization of o-phenylenediamine (o-PD) and dopamine (DA) in the presence of template molecule Glu. The resulting MIP material was characterized with a potentiostatic frequency scan method, cyclic voltammetry, capacitance measurements, atomic force microscopy, and X-ray photoelectron spectroscopy. The structure and recognition behaviour of the copolymer film to template molecule depended on its composition. The optimal composition was at the o-PD to DA molar ratio of 3:2. With a potentiostatic time scan method the copolymer displayed high enantioselectivity and sensitivity to the stereoselective rebinding of L- or D-Glu to their corresponding artificial receptor due to the exact definition of the imprint cavity. The capacitance response of the sensor for L-Glu or D-Glu was proportional to their concentration in the range of 16.7 to 250 μM. The enantiometric selectivity coefficients for L-Glu and D-Glu imprinted films against their respective enantiomers are 24 and 15, respectively. The resulting MIP capacitive sensors showed good reproducibility, stability and repeatability. This strategy opened a convenient way for preparation of enantioselective MIPs and recognition of enantiotropic molecules
Template and target information: glutamic acid, Glu
Author keywords: copolymers, molecular imprinting, sensors

  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner