Authors: Jin GY
, Tang YW
, Liu SZ
, Wang SC
, Xing RK
Preparation and Application of a Novel Silica-Supported Organic-Inorganic Hybrid Molecular Imprinting Polymer.
Publication date: 2008
Journal: Analytical Letters
Alternative URL: http://www.informaworld.com/10.1080/00032710802162103
Abstract: A novel estazolam-imprinted silica sorbent was prepared by the surface imprinting technique using 3-aminopropyltriethoxysilane (APTEOS) and phenyltrimethoxysilane (PTMOS) as functional monomers. The functional monomers are expected to form hydrogen bonds and -Ç--Ç interactions with estazolam. The imprinted silica sorbent was characterized by Fourier transform infrared spectroscopy (FT-IR), element analysis, and scanning electron micrograph (SEM). Compared to C18 solid phase extraction (SPE) and liquid-liquid extraction, molecular imprinting polymer (MIP) SPE was the most feasible method to extract estazolam from human plasma, and the recovery of estazolam was up to 98.7-¦1.2%
Template and target information: estazolam
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