MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Jin GY, Li W, Yu SN, Peng YY, Kong JL
Article Title: Novel superparamagnetic core-shell molecular imprinting microspheres towards high selective sensing.
Publication date: 2008
Journal: Analyst
Volume: 133
Issue: (10)
Page numbers: 1367-1372.
DOI: 10.1039/b802120a

Abstract: Novel superparamagnetic core-shell imprinting microspheres (MCSIMs) were synthesized using magnetite microspheres with 350 nm diameter and 70 nm thickness silica gel to form core-shell Fe3O4/SiO2 composite for template phenylephrine (Phen) recognition and high efficiency separation. Compared to the previous imprinting recognition, the main advantage of this strategy lies in two aspects: one is the high stability and monodispersity of the MCSIMs structure, the other is the use of superparamagnetic Fe3O4/SiO2 microspheres as an immobilization matrix and separation tool, thus greatly simplifying time-consuming washing steps. The affinity and selectivity of the MCSIMs were monitored by QCM and electrochemistry measurements. Imprinting microspheres have a remarkable affinity to Phen over that of structurally related molecules, including DA, EP, Phe and Tyr. The relative binding selectivity for different analytes estimated from amperometric signals was Phen : DA : EP = 40 : 5 : 1. The MCSIMs sensor showed a high sensitivity (400 A mM-1), short response time (reaching 98% within 10 s), and broad linear response range from 1 M to 0.1 mM and low detection limit (0.1 M). Additionally, the results of control experiments showed that only negligible signal was obtained for non-imprinting microspheres. This could be reasonably attributed to the unique surface pores, charges and especially the nature of the functional groups inside MCSIMs cavities.
Template and target information: phenylephrine


  mipdatabase.com logo imprinters do it in bulk shirt  Science Teacher peptide mug  Perpetual student shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner