Book title: Multi-Funtional Materials and Structures, Parts 1 & 2
Editors: Lau AKT, Lu J, Varadan VK, Chang FK, Tu JP, Lam PM
Publisher: Trans Tech Publications Ltd.
Series title: Advanced Materials Research
Volume number: 47-50
Abstract: Molecularly imprinted composite materials (PM) selective to S-naproxen were prepared in the surface of mesoporous silica sphere (SBA-15) by surface imprinting technique. FT-IR, SEM and surface area analysis were used to study the structural morphology of PM and MIPs particles and probe the incorporation of polymer into the SBA-15 framework. The results revealed that PM showed better binding affinity and selectivity to the template molecule than MIPs and the maximum saturated binding capacity of PM to S-naproxen and R-naproxen was about 10.3332 and 6.0063 mu mol.g(-1). Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications Such as chromatographic stationary phases for chiral separations
Template and target information: S-naproxen
Author keywords: molecularly imprinted polymer, surface imprinting, mesoporous silica sphere, S-naproxen