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Reference type: Book Chapter
Authors: Bing NC, Tian Z, Chen SW, Li QH, Xu ZL
Publication date: 2008
Chapter title: Synthesis and characteristic of molecularly imprinted polymer immobilized mesoporous silica sphere for selective binding of S-naproxen.
Page numbers: 890-893.
DOI: 10.4028/www.scientific.net/AMR.47-50.890

Book title: Multi-Funtional Materials and Structures, Parts 1 & 2
Editors: Lau AKT, Lu J, Varadan VK, Chang FK, Tu JP, Lam PM
Publisher: Trans Tech Publications Ltd.
City: Zurich
ISBN: 1022-6680
Series title: Advanced Materials Research
Volume number: 47-50

Abstract: Molecularly imprinted composite materials (PM) selective to S-naproxen were prepared in the surface of mesoporous silica sphere (SBA-15) by surface imprinting technique. FT-IR, SEM and surface area analysis were used to study the structural morphology of PM and MIPs particles and probe the incorporation of polymer into the SBA-15 framework. The results revealed that PM showed better binding affinity and selectivity to the template molecule than MIPs and the maximum saturated binding capacity of PM to S-naproxen and R-naproxen was about 10.3332 and 6.0063 mu mol.g(-1). Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications Such as chromatographic stationary phases for chiral separations
Template and target information: S-naproxen
Author keywords: molecularly imprinted polymer, surface imprinting, mesoporous silica sphere, S-naproxen


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