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Reference type: Journal
Authors: Patel AK, Sharma PS, Prasad BB
Article Title: Development of a Creatinine Sensor Based on a Molecularly Imprinted Polymer-Modified Sol-Gel Film on Graphite Electrode.
Publication date: 2008
Journal: Electroanalysis
Volume: 20
Issue: (19)
Page numbers: 2102-2112.
DOI: 10.1002/elan.200804294

Abstract: An electrochemical creatinine sensor based on a molecularly imprinted polymer (MIP)-modified sol-gel film on graphite electrode was developed. The surface coating of MIP over sol-gel was advantageous to obtain a porous film with outwardly exposed MIP cavities for unhindered selective rebinding of creatinine from aqueous and biological samples. A fast differential pulse, cathodic stripping voltammetric response of creatinine can be obtained after being preanodized the sensor in neutral medium containing appropriate amount of creatinine at +1.8 V versus SCE for 120 s. A linear response over creatinine concentration in the range of 1.23 to 100 mug mL-1 was exhibited with a detection limit of 0.37 mug mL-1 (S/N=3)
Template and target information: creatinine
Author keywords: Creatinine sensor, molecularly imprinted polymer, sol-gel, Graphite electrode, differential pulse, Cathodic stripping voltammetry


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