Authors: Nemoto K
, Nomachi M
, Kubo T
, Sano T
, Hosoya K
, Kaya K
Development of the novel separation media having 3D structural recognition ability for domoic acid.
Publication date: 2006
Alternative URL: http://sciencelinks.jp/j-east/display.php?id=000020062406A0875423
Abstract: We prepared the molecularly imprinted polymers for an amnesic shellfish poison, domoic acid. To prepare the polymer, several commercial di- and/or tricarboxylic compounds used for templates. The results suggested that the highest selective recognition ability for domoic acid was found when 1,3,5-pentane tricarboxylic acid was used as the template, and 3D structural recognition ability was expressed due to the similarity of the structure around the carboxylic acids of domoic acid and the templates. In addition, we obtained agreeable results of structural calculation that supported our experimental result. (author abst.)
Template and target information: domoic acid
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