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Abstract: Although the field of controlled delivery in pharmaceutical and consumer products has grown exponentially throughout the past decade, most classical controlled-release systems provide only passive release. Some may release due to a change in temperature, and some may rupture due to applied pressure, but few if any can actually respond to the presence of one specific molecule in its environment and release its contents in response to that molecule and that molecule alone. The unique use of molecular imprinting in the AffinimerGäó delivery systems allows that sensitivity to become reality